PMS77 Real-World Comparison of Health Care Utilization Between Duloxetine Initiators and Pregabalin Initiators Among Fibromyalgia Patients

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Real-world comparison of health care utilization between duloxetine and pregabalin initiators with fibromyalgia

OBJECTIVES To compare health care utilization of duloxetine initiators and pregabalin initiators among fibromyalgia patients in a real-world setting. METHODS A retrospective cohort study was conducted based on a US national commercial health claims database (2006-2009). Fibromyalgia patients who initiated duloxetine or pregabalin in 2008, aged 18-64 years, and who maintained continuous health...

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Comparing common reasons for inpatient and outpatient visits between commercially-insured duloxetine or pregabalin initiators with fibromyalgia

BACKGROUND The purpose of this study was to examine the main reasons for inpatient or outpatient visits after initiating duloxetine or pregabalin. METHODS Commercially insured patients with fibromyalgia and aged 18-64 years who initiated duloxetine or pregabalin in 2006 with 12-month continuous enrollment before and after initiation were identified. Duloxetine and pregabalin cohorts with simi...

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Patterns of health care utilization related to initiation of amitriptyline, duloxetine, gabapentin, or pregabalin in fibromyalgia

INTRODUCTION Several pharmacologic treatments are available for fibromyalgia, but little is known about the comparative effectiveness of these treatments on health care utilization. METHODS Using US commercial insurance claims data (covering 2007 to 2009), we conducted a cohort study to examine the comparative effectiveness of amitriptyline, duloxetine, gabapentin, and pregabalin on health ca...

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Impact of potential pregabalin or duloxetine drug–drug interactions on health care costs and utilization among Medicare members with fibromyalgia

PURPOSE To examine the impact of newly initiated pregabalin or duloxetine treatment on fibromyalgia (FM) patients' encounters with potential drug-drug interactions (DDIs), the health care cost and utilization consequences of those interactions, and the impact of treatment on opioid utilization. PATIENTS AND METHODS Subjects included those with an FM diagnosis, a pregabalin or duloxetine presc...

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Tritylium ions as initiators and co-initiators in cationic polymerizations

On the other hand, the less stabilized tris(4chlorophenyl)methyl cation (1 b) was reported to initiate the polymerization of isobutene3). In accordance, p-methoxy and p-methyl substituted tritylium ions do not initiate the polymerization of a-methylstyrene, in contrast to the less stable 1 a and 1 b4). Only for few reactive monomers, however, the initiation was proven to proceed via addition of...

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ژورنال

عنوان ژورنال: Value in Health

سال: 2012

ISSN: 1098-3015

DOI: 10.1016/j.jval.2012.08.1432